Tetrahedron Letters

The allyloxycarbonylaminomethyl group: a new allytic protection for the thiol group of cysteine

AM Kimbonguila, A Merzouk, F Guibé, A Loffet

Index: Kimbonguila, Andre Malanda; Merzouk, Ahmed; Guibe, Francois; Loffet, Albert Tetrahedron Letters, 1994 , vol. 35, # 48 p. 9035 - 9038

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Citation Number: 12

Abstract

Abstract S-Allocam derivatives of thiols in general and cysteine in particular are selectively and readily deprotected through palladium catalyzed hydrostannolysis. They are perfectly stable in the basic conditions of Fmoc-removal, but only marginally stable in the acidic conditions of t-Bu, Boc removal.