Computational and DNMR Analysis of the Conformational Isomers and Stereodynamics of Secondary 2, 2′-Bisanilides

…, M Chiarucci, L Prati, KW Bentley, C Wolf

Index: Mazzanti, Andrea; Chiarucci, Michel; Bentley, Keith W.; Wolf, Christian Journal of Organic Chemistry, 2014 , vol. 79, # 8 p. 3725 - 3730

Full Text: HTML

Citation Number: 1

Abstract

The conformational preference of 2, 2′-bisanilides was investigated by variable- temperature NMR spectroscopy, NMR titration and diffusion experiments, IR spectroscopy, computational analysis, and X-ray crystallography. The formation of a conformation having the two amide moieties linked by an intramolecular hydrogen bond was detected at low temperatures. The interconversion kinetics of the two conformational species of bisanilide ...