Evaluation of animal liver acetone powders for the resolution of 1, 2, 3, 4-tetrahydroisoquinoline-3-carboxylic acid

R Sánchez, H Luna, HI Pérez, N Manjarrez…

Index: Sanchez, Remedios; Luna, Hector; Perez, Herminia I.; Manjarrez, Norberto; Solis, Aida Tetrahedron Asymmetry, 2001 , vol. 12, # 10 p. 1399 - 1401

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Citation Number: 10

Abstract

Butyl, ethyl and methyl esters of 1, 2, 3, 4-tetrahydroisoquinoline-3-carboxylic acid were hydrolyzed stereoselectively under very mild conditions to give the corresponding (S)-acid and the unreacted (R)-ester using readily available animal liver (chicken, mouse, rat and rabbit) acetone powders.