Arkivoc

An expedient synthesis of novel 2-substituted thiazolo [4, 5-f] isoquinolines/quinolines and benzo [1, 2-d: 4, 3-d′] bisthiazoles and their potential as inhibitors of …

M Chakrabarty, A Mukherji, S Karmakar, R Mukherjee…

Index: Chakrabarty, Manas; Mukherji, Ajanta; Karmakar, Sulakshana; Mukherjee, Ratna; Nagai, Kenichiro; Geronikaki, Athina; Elenic, Pitta Arkivoc, 2010 , vol. 2010, # 11 p. 265 - 290

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Citation Number: 4

Abstract

Abstract An efficient, general synthesis of 2-substituted thiazolo [4, 5-f] isoquinolines, thiazolo [4, 5-f]-quinolines and benzo [1, 2-d: 4, 3-d'] bisthiazoles has been accomplished from 5-nitroisoquinoline/quinoline and 6-nitrobenzothiazole, respectively, and all the products have been thoroughly identified spectroscopically (IR, 1H and 13C NMR, LR/HR EI/FAB/ESI-MS). The synthesis of thiazolo [4, 5-f] isoquinolines constitutes the first ...