Organic & biomolecular chemistry

Chemiluminescence from alkoxy-substituted acridinium dimethylphenyl ester labels

A Natrajan, D Sharpe, D Wen

Index: Natrajan, Anand; Sharpe, David; Wen, David Organic and Biomolecular Chemistry, 2012 , vol. 10, # 17 p. 3432 - 3447

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Citation Number: 11

Abstract

Chemiluminescent acridinium dimethylphenyl ester labels are used in automated immunoassays for clinical diagnostics. Light emission from these labels is triggered by alkaline peroxide in the presence of the cationic surfactant cetyltrimethylammonium chloride (CTAC). The surfactant plays a critical role in the chemiluminescence process of these labels by both accelerating their emission kinetics and increasing total light output ...