Ruthenium??catalyzed formal alkyl group transfer: Synthesis of quinolines from nitroarenes and alkylammonium halides

…, NY Lee, TJ Kim, SC Shim

Index: Cho, Chan Sik; Lee, Na Young; Kim, Tae-Jeong; Shim, Sang Chul Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 3 p. 423 - 429

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Citation Number: 5

Abstract

Abstract Nitroarenes are reductively cyclized with an array of tetraalkylammonium halides and trialkylarnmonium chlorides in the presence of a catalytic amount of a ruthenium catalyst along with tin (II) chloride dihydrate at 180 to afford the corresponding quinolines in moderate to good yields. The addition of tin (II) chloride dihydrate is necessary for the effective formation of quinolines and toluene is the solvent of choice. A reaction pathway ...