Ailanthoidol derivatives and their anti-inflammatory effects

NL Lee, JJ Lee, JK Kim, JG Jun

Index: Lee, Na Li; Lee, Jae Jun; Kim, Jin-Kyung; Jun, Jong-Gab Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 6 p. 1907 - 1912

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Citation Number: 4

Abstract

Abstract Ailanthoidol showed a strong-inflammatory effect in a previous result. Ailanthoidol derivatives were prepared for the-inflammatory test using Sonogashira coupling, iodine induced cyclization and Wittig reaction.-inflammatory effects of the prepared ailanthoidol derivatives were examined in lipopolysaccharide (LPS)-stimulated RAW 264-7 macrophages. The results showed that some ailanthoidol derivatives inhibited ...