Journal of the American Chemical Society

Studies on the molybdenum cofactor. An unequivocal total synthesis of (.+-.)-urothione

EC Taylor, LA Reiter

Index: Taylor; Reiter Journal of the American Chemical Society, 1989 , vol. 111, # 1 p. 285 - 291

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Citation Number: 35

Abstract

Abstract: Urothione, the urinary metabolite of the molybdenum cofactor, has been synthesized in racemic form in 10 steps from pyrazine 3 in 19% overall yield. Thus, a thiophene ring was fused to pyrazine 3 to give a thieno [2, 3-b] pyrazine (14) which ...