Tetrahedron

A new stereoselective synthesis of chiral γ-functionalized (E)-allylic amines

G Reginato, A Mordini, F Messina, A Degl'Innocenti…

Index: Reginato, Gianna; Mordini, Alessandro; Messina, Flavia; Degl'Innocenti, Alessandro; Poli, Giovanni Tetrahedron, 1996 , vol. 52, # 33 p. 10985 - 10996

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Citation Number: 45

Abstract

Chiral t-Boc protected propargylic amines have been obtained starting from aminoaldehydes derived from natural aminoacids. Stannylcupration of these substrates affords an easy regio-and stereocontrolled route to the corresponding γ-stannylated (E)- allylamines which are useful intermediates for the synthesis of the corresponding γ- funtionalized allylic systems.

~83%

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