Nitroethylene as a versatile ketene equivalent. Novel one-step preparation of prostaglandin intermediates by reduction and abnormal nef reaction

S Ranganathan, D Ranganathan…

Index: Ranganathan,S. et al. Journal of the American Chemical Society, 1974 , vol. 96, p. 5261 - 5262

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Citation Number: 48

Abstract

This communication presents, inter alia, the novel, convenient, facile one-step preparation of prostaglandin intermediates I1 and 111 from the nitroethylene adduct I. The I-I1 change represents the simplest entry to the prostanoid A nucleus and the lactone I1 is a key intermediate in the recently developed synthesis of A