Tetrahedron letters

A straightforward method for the synthesis of unsymmetrically substituted 1, 3-diynes

V Fiandanese, D Bottalico, G Marchese, A Punzi

Index: Fiandanese, Vito; Bottalico, Daniela; Marchese, Giuseppe; Punzi, Angela Tetrahedron Letters, 2003 , vol. 44, # 51 p. 9087 - 9090

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Citation Number: 31

Abstract

An efficient synthetic approach to a variety of unsymmetrically substituted conjugated diynes has been developed, starting from the readily available 1, 4-bis (trimethylsilyl)-1, 3- butadiyne, based upon the selective and sequential substitution of the trimethylsilyl groups with alkyl, aryl and vinyl groups.