Aerobic Oxidative Coupling between Carbon Nucleophiles and Allylic Alcohols: A Strategy to Construct β??(Hetero) Aryl Ketones and Aldehydes through Hydrogen …

L Huang, J Qi, X Wu, W Wu…

Index: Huang, Liangbin; Qi, Ji; Wu, Xia; Wu, Wanqing; Jiang, Huanfeng Chemistry - A European Journal, 2013 , vol. 19, # 46 p. 15462 - 15466

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Citation Number: 13

Abstract

Since the early 1970s, the Pd-catalyzed Heck reaction has become a powerful tool to prepare substituted olefins.[1, 2] The main challenges in the intermolecular Heck reaction are controlling the regioselectivity and high selective β-H elimination when olefins without a significant electronic difference at the two olefinic sites are used as the substrates.[3] The groups of Stahl and Zhou recently reported ligand-controlled regioselectivity in the ...