Study of some thiophene analogs of glycolic acid

…, AW Springsteen, DWH MacDowell

Index: Jeffries, Alfred T.; Moore, Kenneth C.; Ondeyka, Debra M.; Springsteen, Arthur W.; MacDowell, Denis W.H. Journal of Organic Chemistry, 1981 , vol. 46, # 14 p. 2885 - 2889

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Citation Number: 28

Abstract

Reaction of phenyl (3-thieny1) glycolic acid (1) with A1C13 in benzene solution leads to the formation of 4H-indeno [1, 2-b] thiophene4-carboxylic acid (2) whereas analogous reaction of phenyl@-thieny1) glycolic acid (4) produces no indenothiophene but only a mixture of 5 and 6. In the case of di-(24hienyl) glycolic acid (14b) and di43-thieny1) glycolic acid (16b) analogous results are obtained, with the former leading to the formation of 15 and the ...