Tetrahedron letters

Facile synthesis of substituted dihydro-1, 4-dithiins and-1, 4-dithiepins from α-oxo ketene cyclic dithioacetals

D Dong, R Sun, H Yu, Y Ouyang, Q Zhang, Q Liu

Index: Dong, Dewen; Sun, Ran; Yu, Haifeng; Ouyang, Yan; Zhang, Qian; Liu, Qun Tetrahedron Letters, 2005 , vol. 46, # 43 p. 7331 - 7335

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Citation Number: 12

Abstract

Recently, we developed a novel thioacetalization reaction using nonthiolic odorless cyclic ketene dithioacetals, for example, 2-(2-chloro-1-(1-chloroethenyl)-2-propenylidene)-1,3-dithiane and 3-(1,3-dithian-2-ylidene)pentane-2,4-dione, as 1,3-propanedithiol equivalents. 17 During the course of our studies on the thioacetalization of α-bromo/hydroxy carbonyl compounds using 2-(1,3-dithiolan/dithian-2-ylidene)-3-oxobutanoic acids 1a/1b as dithiol equivalents, ...