The Journal of organic chemistry

A Practical, Two-Step Synthesis of 2-Substituted 1, 3-Butadienes

S Sen, S Singh, SMN Sieburth

Index: Sen, Sushmita; Singh, Swapnil; Sieburth, Scott McN Journal of Organic Chemistry, 2009 , vol. 74, # 7 p. 2884 - 2886

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Citation Number: 8

Abstract

One of the fundamental building blocks of organic chemistry is the 1,3-diene.(1) Butadienes substituted at C-2 are a pivotal component of our new method for constructing optically active 3-alkyl-4-silyl -1-butenes, but few 2-alkyl-1,3-butadienes are commercially available.(2) A broad set of methods have been described for preparation of substituted 1,3-dienes;(3, 4) however, a review of these procedures with a goal of generating simple 2-substituted derivatives in multigram ...

Stannes in synthesis: A new route to 2-substituted-1, 3-buta...

[Ueno, Yoshio; Sano, Hiroshi; Aoki, Seiichi; Okawara, Makoto Tetrahedron Letters, 1981 , vol. 22, # 28 p. 2675 - 2678]

α-haloalkanesulfonyl bromides in organic synthesis. 4. Regio...

[Block, Eric; Eswarakrishnan, Venkatachalam; Gebreyes, Kassu Tetrahedron Letters, 1984 , vol. 25, # 48 p. 5469 - 5472]

A Practical, Two-Step Synthesis of 2-Substituted 1, 3-Butadi...

[Brown, Paul A.; Bonnert, Roger V.; Jenkins, Paul R.; Lawrence, Nicholas J.; Selim, Mohammed R. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 8 p. 1893 - 1900]