Dehydropeptides, containing α,β-unsaturated amino acid (or dehydroamino acid) moiety, are typical abnormal peptides. 1 Their structures are rigid and reactive because they have a double bond conjugated with a peptide linkage. In a previous study on the design of artificial peptides, the introduction of dehydroamino acid residues into normal peptides induced folded conformations based on structural factors. 2 A number of dehydropeptides are bioactive ...
