e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
First asymmetric synthesis of dihydrobenzo [c] phenanthrene-1, 4-quinones with helical chiralityElectronic supplementary information (ESI) available: experimental …
…, S García-Cerrada, MJ Sanz-Cuesta…
Index: Carreno; Garcia-Cerrada; Sanz-Cuesta; Urbano Chemical Communications, 2001 , # 16 p. 1452 - 1453
The first enantioselective synthesis of 12-tert-butyl substituted 7, 8-dihydrobenzo [c] phenanthrene-1, 4-quinones having helical chirality is achieved with good chemical and optical yields through a domino Diels–Alder reaction–sulfoxide elimination–oxidation process starting from enantiopure (S)-2-(p-tolylsulfinyl)-1, 4-benzoquinone and 5-tert-butyl substituted 3-vinyl-1, 2-dihydronaphthalenes as dienes.
