Journal of organometallic chemistry

Metal complexes of biologically important ligands, Part CXVIII. Metathesis of dehydro amino acids with Fischer carbene complexes: synthesis of complexes of amino …

H Dialer, K Polborn, W Beck

Index: Dialer, Harald; Polborn, Kurt; Beck, Wolfgang Journal of Organometallic Chemistry, 1999 , vol. 589, # 1 p. 21 - 28

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Citation Number: 10

Abstract

Metathesis of N-protected dehydro alanine esters with Fischer carbene complexes affords α- amino acid metal carbenes O (CH2CH2) 2N C [ M (CO) 5](CO2Me)(3) and Ph2C N C [ M (CO) 5](CO2Et)(6)(M= Cr, Mo, W). The X-ray structural analysis of 6c shows the dominance of the zwitterionic form Ph2C N C [M (CO) 5](CO2Et) in these complexes. Labeling of peptides by the M (CO) 5 fragment is demonstrated by the synthesis of Ph2C ...