Structure-functional analysis of interactions of terminal deoxynucleotidyl transferase with new non-nucleoside substrates

…, IA Vasiliev, VL Lapteva, AL Khandazhinskaya…

Index: Matyugina; Alexandrova; Jasco; Ivanov; Vasiliev; Lapteva; Khandazhinskaya; Kukhanova Russian Journal of Bioorganic Chemistry, 2009 , vol. 35, # 3 p. 342 - 348

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Abstract

Abstract New non-nucleoside esters of phosphoric acid containing various hydrophobic groups, namely (1) N-(2-tripticencarbonyl)-4-aminobutyl;(2) 5-phenylsubstituted N-(2, 4- dinitrophenyl)-4-aminobutyl;(3) N-(4-phenylbenzoyl)-and N-(4-(N-benzylamino) benzoyl)-2- aminoethyl groups, as well as (4) diphenylmethyl and fluorenyl groups were synthesized and studied as substrates of terminal deoxynucleotidyl transferase. With the exception of ...