e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
. beta.-Lactams. 3. Asymmetric total synthesis of new non-natural 1. beta.-methylcarbapenems exhibiting strong antimicrobial activities and stability against human …
Y Nagao, Y Nagase, T Kumagai…
Index: Journal of Organic Chemistry, , vol. 57, # 15 p. 4243 - 4249
... Chem., Vol. ... 0.1 M phosphate buffer (pH 7.0), 1 N NaOH, 0 "C; (9) HP-40 column, acetone-H20 (3:97); (h) lyophyli- zation (44% from 31); (i) aqueous MeOH solution of 32 and 1 N NaOH; (j) THF-0.35 M ... The organic portion was washed with brine, dried, and evaporated in uacuo. ...
![4-nitrobenzyl (4R,5R,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-3,7-dioxo-1-azabicyclo[3.2.0]-heptane-2-carboxylate Structure](https://image.chemsrc.com/caspic/055/104873-15-6.png)
![p-Nitrobenzyl (1R,5S,6S)-2-[[(N,N-Bis(p-nitrobenzyloxycarbonyl)pyrazolidin-4-yl]thio]-6-[(1R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylate Structure](https://image.chemsrc.com/caspic/071/120764-68-3.png)