Iodide-catalyzed reductions: development of a synthesis of phenylacetic acids

…, RD Larsen, JA Murry

Index: Milne, Jacqueline E.; Murry, Jerry A.; King, Anthony; Larsen, Robert D. Journal of Organic Chemistry, 2009 , vol. 74, # 1 p. 445 - 447

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Citation Number: 20

Abstract

A new convenient and scalable synthesis of phenylacetic acids has been developed via the iodide catalyzed reduction of mandelic acids. The procedure relies on in situ generation of hydroiodic acid from catalytic sodium iodide, employing phosphorus acid as the ...