Substituted furans as inhibitors of the PDE4 enzyme

…, R Rasori, A Robichaud, Y Girard, D Macdonald

Index: Perrier, Helene; Bayly, Christopher; Laliberte, France; Huang, Zheng; Rasori, Roberta; Robichaud, Annette; Girard, Yves; Macdonald, Dwight Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 3 p. 323 - 326

Full Text: HTML

Citation Number: 24

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The synthesis and in vitro activity of a series of substituted furans as a novel structural class of PDE4 inhibitors is described. Comparison of emetic threshold with known PDE4 inhibitors is presented. ... The synthesis and the in vitro activity of a series of substituted furans as a ...

4393-06-0

3-Phenylpropene-3-ol

Synthetic Utility of Stannyl Enolates as Radical Alkylating ...

[Miura, Katsukiyo; Fujisawa, Naoki; Saito, Hiroshi; Wang, Di; Hosomi, Akira Organic Letters, 2001 , vol. 3, # 16 p. 2591 - 2594]

A new strategy for 1, 4-and 1, 4, 7-polycarbonyl compounds

[Sato, Tsuneo; Okazaki, Hiroshi; Otera, Junzo; Nozaki, Hitosi Journal of the American Chemical Society, 1988 , vol. 110, # 15 p. 5209 - 5211]

Conjugate reduction of 2-butene-1, 4-diones with LiAlH4-SbCl...

[Sayama, Shinsei; Inamura, Yutaka Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 1 p. 306 - 308]

From alkenylsilanes to ketones with air as the oxidant

[Kondo, Junichi; Shinokubo, Hiroshi; Oshima, Koichiro Angewandte Chemie - International Edition, 2003 , vol. 42, # 7 p. 825 - 827]

Revisiting a Classic Approach to the Aspidosperma Alkaloids:...

[Vankar, Yashwant D.; Kumaravel, G.; Mukherjee, Neeta; Rao, C. Trinadha Synthetic Communications, 1987 , vol. 17, # 2 p. 181 - 188]