Study on selectin blocker. 8. Lead discovery of a non-sugar antagonist using a 3D-pharmacophore model

Y Hiramatsu, T Tsukida, Y Nakai, Y Inoue…

Index: Journal of Medicinal Chemistry, , vol. 43, # 8 p. 1476 - 1483

Full Text: HTML

Citation Number: 31

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. For the syntheses of compounds 3 and 4, the condensation of 5a,b with p-nitrobenzoyl chloride in the presence of triethylamine in chloroform afforded compounds 6a,b, in 54−73% yields. ...