Tetrahedron Letters

Synthesis of N-benzothiazol-2-yl-amides by a copper-catalyzed intramolecular cyclization process

J Wang, F Peng, J Jiang, Z Lu, L Wang, J Bai, Y Pan

Index: Wang, Junke; Peng, Feng; Jiang, Ju-li; Lu, Zhi-jin; Wang, Le-yong; Bai, Junfeng; Pan, Yi Tetrahedron Letters, 2008 , vol. 49, # 3 p. 467 - 470

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Citation Number: 61

Abstract

Employing N-(4, 5-dihydrooxazol-2-yl) benzamide as novel and efficient ligand, the copper- catalyzed intramolecular cyclization of various substituted 1-acyl-3-(2-bromophenyl) thioureas could be successfully carried out under mild conditions. A variety of N- benzothiazol-2-yl-amides were synthesized in good to excellent yields.