e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Antiallergic agents. 3. N-(1H-tetrazol-5-yl)-2-pyridinecarboxamides

Y Honma, K Hanamoto, T Hashiyama…

Index: Honma; Hanamoto; Hashiyama; et al. Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 125 - 128

Full Text: HTML

Citation Number: 18

Abstract

A series of N-tetrazolylpyridinecarboxamides was prepared and evaluated for antiallergic activity by the passive cutaneous anaphylaxis (PCA) assay. From the structure-activity relationships (SAR) of this class of compounds, it was revealed that the N- ...

Ethoxalyl chloride Structure

Ethoxalyl chloride

6-(2-phenylethenyl)pyridin-2-amine Structure

6-(2-phenylethe...

~87%

ethyl 2-oxo-2-[[6-(2-phenylethenyl)pyridin-2-yl]amino]acetate Structure

ethyl 2-oxo-2-[...

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6-(2-phenylethenyl)pyridine-2-carbonitrile Structure

6-(2-phenylethe...

~%

ethyl 2-oxo-2-[[6-(2-phenylethenyl)pyridin-2-yl]amino]acetate Structure

ethyl 2-oxo-2-[...

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(E)-2-(α-styryl)pyridine 1-oxide Structure

(E)-2-(α-styryl...

~%

ethyl 2-oxo-2-[[6-(2-phenylethenyl)pyridin-2-yl]amino]acetate Structure

ethyl 2-oxo-2-[...

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6-(2-phenylethenyl)pyridine-2-carboxylic acid Structure

6-(2-phenylethe...

~%

ethyl 2-oxo-2-[[6-(2-phenylethenyl)pyridin-2-yl]amino]acetate Structure

ethyl 2-oxo-2-[...

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ethyl 2-oxo-2-[[6-(2-phenylethenyl)pyridin-2-yl]amino]acetate Structure

ethyl 2-oxo-2-[...

~47%

2-oxo-2-[[6-(2-phenylethenyl)pyridin-2-yl]amino]acetic acid Structure

2-oxo-2-[[6-(2-...

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6-(2-phenylethenyl)pyridine-2-carbonitrile Structure

6-(2-phenylethe...

~%

2-oxo-2-[[6-(2-phenylethenyl)pyridin-2-yl]amino]acetic acid Structure

2-oxo-2-[[6-(2-...

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(E)-2-(α-styryl)pyridine 1-oxide Structure

(E)-2-(α-styryl...

~%

2-oxo-2-[[6-(2-phenylethenyl)pyridin-2-yl]amino]acetic acid Structure

2-oxo-2-[[6-(2-...

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6-(2-phenylethenyl)pyridine-2-carboxylic acid Structure

6-(2-phenylethe...

~%

2-oxo-2-[[6-(2-phenylethenyl)pyridin-2-yl]amino]acetic acid Structure

2-oxo-2-[[6-(2-...

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6-(2-phenylethenyl)pyridin-2-amine Structure

6-(2-phenylethe...

~%

2-oxo-2-[[6-(2-phenylethenyl)pyridin-2-yl]amino]acetic acid Structure

2-oxo-2-[[6-(2-...

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6-(2-phenylethenyl)pyridine-2-carbonitrile Structure

6-(2-phenylethe...

~60%

2-(2-phenylethenyl)-6-(2H-tetrazol-5-yl)pyridine Structure

2-(2-phenylethe...

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(E)-2-(α-styryl)pyridine 1-oxide Structure

(E)-2-(α-styryl...

~%

2-(2-phenylethenyl)-6-(2H-tetrazol-5-yl)pyridine Structure

2-(2-phenylethe...

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6-(2-phenylethenyl)pyridine-2-carbonitrile Structure

6-(2-phenylethe...

~%

6-(2-phenylethenyl)pyridine-2-carboxylic acid Structure

6-(2-phenylethe...

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(E)-2-(α-styryl)pyridine 1-oxide Structure

(E)-2-(α-styryl...

~%

6-(2-phenylethenyl)pyridine-2-carboxylic acid Structure

6-(2-phenylethe...

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6-Chloropicolinic acid Structure

6-Chloropicolin...

~%

6-CHLORO-PYRIDINE-2-CARBONYL CHLORIDE Structure

6-CHLORO-PYRIDI...

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4-Methoxy-2-pyridinecarboxylic acid Structure

4-Methoxy-2-pyr...

~%

2-Pyridinecarbonyl chloride, 4-methoxy- (9CI) Structure

2-Pyridinecarbo...

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Sodium cyanide Structure

(E)-2-(α-styryl)pyridine 1-oxide Structure

(E)-2-(α-styryl...

~%

6-(2-phenylethenyl)pyridine-2-carbonitrile Structure

6-(2-phenylethe...

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6-(2-phenylethenyl)pyridine-2-carboxylic acid Structure

6-(2-phenylethe...

tert-Butanol Structure

~25%

2-((tert-butoxycarbonyl)amino)-6-styrylpyridine Structure

2-((tert-butoxy...

6-(2-phenylethenyl)pyridin-2-amine Structure

6-(2-phenylethe...

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6-(2-phenylethenyl)pyridine-2-carbonitrile Structure

6-(2-phenylethe...

~%

6-(2-phenylethenyl)pyridin-2-amine Structure

6-(2-phenylethe...

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(E)-2-(α-styryl)pyridine 1-oxide Structure

(E)-2-(α-styryl...

~%

6-(2-phenylethenyl)pyridin-2-amine Structure

6-(2-phenylethe...

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