Heterocycles

Concise and versatile synthesis of N-arylalkylpiperidine as potential intermediates for 4-anilidopiperidine analgesics

YG Suh, DY Shin, KH Cho, JS Ryu

Index: Suh, Young-Ger; Shin, Dong-Yun; Cho, Kyung-Ho; Ryu, Jae-Sang Heterocycles, 1998 , vol. 48, # 2 p. 239 - 242

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Citation Number: 4

Abstract

Abstract-N-Arylalkylpiperidones and N-arylalkylspiroepoxypiperidine as potential intermediates for 4—anilidbpiperidine analgesics and their structural analogues have been efficiently synthesized from the simple arylalkylamines by two and three step sequences respectively.

~81%

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