Rearrangement of Differentially Protected N??Arylhydroxylamines

…, MD Woodrow, NCO Tomkinson

Index: Porzelle, Achim; Woodrow, Michael D.; Tomkinson, Nicholas C. O. European Journal of Organic Chemistry, 2008 , # 30 p. 5135 - 5143

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Citation Number: 8

Abstract

Abstract The rearrangement of a series of N, O-difunctionalised N-arylhydroxylamines to generate protected 2-aminophenols has been investigated. N-Boc-N-Aryl-O- acylhydroxylamines are stable, isolable compounds which rearrange smoothly at temperatures between 110 and 140 C. The corresponding N-Boc-N-aryl-O- sulfonylhydroxylamines were not isolated and rearrange to 1, 2-difunctionalised ...