Catalytic aerobic oxidation of substituted 8-methylquinolines in Pd II-2, 6-pyridinedicarboxylic acid systems

J Zhang, E Khaskin, NP Anderson, PY Zavalij…

Index: Zhang, Jing; Khaskin, Eugene; Anderson, Nicholas P.; Zavalij, Peter Y.; Vedernikov, Andrei N. Chemical Communications, 2008 , # 31 p. 3625 - 3627

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Citation Number: 63

Abstract

The ability of PdII complexes derived from 2, 6-pyridinedicarboxylic acids to catalyze homogeneous regioselective aerobic oxidation of 5-and 6-substituted 8-methylquinolines in AcOH–Ac2O solution to produce corresponding 8-quinolylmethyl acetates in high yield was demonstrated; corresponding 8-quinoline carboxylic acids are minor reaction products.