Organic letters

Appending a Tris-imidazole Ligand with a Tyr244 Mimic on the Distal Face of Bromoacetamidoporphyrin

JP Collman, RA Decréau, S Costanzo

Index: Collman, James P.; Decreau, Richard A.; Costanzo, Simona Organic Letters, 2004 , vol. 6, # 6 p. 1033 - 1036

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Citation Number: 24

Abstract

Bromoacetamidoporphyrin is a convenient synthon for the attachment of distal superstructures at room temperature in good yields. New models are presented that contain a tris-imidazole distal ligand set bound to the porphyrin in either a binary or trinary fashion. More importantly, one distal imidazole is cross-linked to a phenol mimicking Tyr244, making this model the closest structural analogue yet reported of the metal free cytochrome c ...