Tetrahedron letters

Synthesis of the ravidomycin ring system

TC McKenzie, W Hassen

Index: McKenzie; Hassen Tetrahedron Letters, 1987 , vol. 28, # 23 p. 2563 - 2566

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Citation Number: 9

Abstract

Abstract Synthesis of the tetracyclic aromatic ring system of the ravidomycin family of anti- tumor agents is reported. The synthesis is a sequential Meerwein and Diels-Alder route with the crucial regiochemistry of the Diels-Alder reaction controlled with a chlorine atom.