Tetrahedron letters

Ionic liquid-promoted dehydration of aldoximes: a convenient access to aromatic, heteroaromatic and aliphatic nitriles

D Saha, A Saha, BC Ranu

Index: Saha, Debasree; Saha, Amit; Ranu, Brindaban C. Tetrahedron Letters, 2009 , vol. 50, # 44 p. 6088 - 6091

Full Text: HTML

Citation Number: 27

Abstract

A simple and convenient procedure for the synthesis of nitriles by dehydration of aldoximes using an ionic liquid, 1-pentyl-3-methylimidazolium tetrafluoroborate,[pmim] BF4 under organic solvent-free condition, has been developed. A variety of aromatic, heteroaromatic and aliphatic aldoximes are converted to the corresponding nitriles. The ionic liquid is recovered and reused for subsequent reactions.

~74%

Convergent synthetic routes to orthogonally fused conjugated...

[Wu, Ruilian; Schumm, Jeffry S.; Pearson, Darren L.; Tour, James M. Journal of Organic Chemistry, 1996 , vol. 61, # 20 p. 6906 - 6921]

Synthesis of Tetrahydropyran??4??ones and Thiopyran??4??ones...

[Rosiak, Anna; Frey, Wolfgang; Christoffers, Jens European Journal of Organic Chemistry, 2006 , # 17 p. 4044 - 4054]

A convenient route to alkynes via phase transfer catalysis: ...

[Dehmlow, Eckehard V.; Lissel, Manfred Tetrahedron, 1981 , vol. 37, p. 1653 - 1658]

One-Pot, Two-Step Conversion of Aldehydes to Phosphonyl-and ...

[Kumar, Rahul; Verma, Deepti; Mobin, Shaikh M.; Namboothiri, Irishi N. N. Organic Letters, 2012 , vol. 14, # 16 p. 4070 - 4073]

Reaction of phosphorus pentachloride with 2-acetylthiophene ...

[Kagan, Jaques; Arora, Sudershan K.; Bryzgis, Marius; Dhawan, Som N.; Reid, Kevin; et al. Journal of Organic Chemistry, 1983 , vol. 48, # 5 p. 703 - 706]