Synthesis of regioisomeric naphtho-furans via naphthyloxyalkanals

…, M Witczak, M Kowalewska, M Augustyniak

Index: Kwiecien; Witczak; Kowalewska; Augustyniak Chemistry of Heterocyclic Compounds, 2010 , vol. 46, # 1 p. 20 - 29

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Citation Number: 6

Abstract

A new route to the regioisomeric 2-alkylnaphtho [2, 1-b]-and 2-alkylnaphtho [1, 2-b] furans via acid-catalyzed cyclization of the corresponding 2-naphthyloxyalkanals under mild conditions over Amberlyst 15 resin has been described. The 2-naphthyloxyalkanals were obtained by palladium-catalyzed reduction of 2-naphthyloxyalkanoyl chlorides.