The Journal of Organic Chemistry

N-Amidoyliminium ion cyclizations. Synthesis of annulated imidazolidinones

H Kohn, ZK Liao

Index: Kohn, Harold; Zeng-Kun Liao Journal of Organic Chemistry, 1982 , vol. 47, # 14 p. 2787 - 2789

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Citation Number: 29

Abstract

4 5 a, R,= C, H,(CH,),; b, R,= 3, 4-(ocH,), c, H,(cH,),; c, R,= 3-(OCH,) C, H, CH,; d, R,= 3- (OCH,) C, H,(CH,),; e, R,= If methoxyphenethyl bromide: m-methoxybenzyl hlaride,~ and (m- methoxypheny1) propyl bromide,'respectively, under basic conditions (KOH/Me2S0, 2 days) gave the corresponding 3-substituted hydantoins 4a-d in moderate yields (5543%). Reduction of 4a-d with excess lithium aluminum hydride (THF, room temperature, 2 days) ...