Design and synthesis of antifungal benzoheterocyclic derivatives by scaffold hopping

C Sheng, X Che, W Wang, S Wang, Y Cao…

Index: European Journal of Medicinal Chemistry, , vol. 46, # 5 p. 1706 - 1712

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Citation Number: 35

Abstract

... European Journal of Medicinal Chemistry. ... rt, 10–30min 1 0–25%; f. 2-aminobenzenethiol, CH 2 Cl 2 , 0 °C∼ rt, 67.8%; g. 1-bromide alkylamine, K 2 CO 3 , MeOH, rt, 10–30min, 15–20%; h. formic anhydride, reflux, 5h, 68.2%; i. formamide, 150 °C, 7h, 75.5%; j. 1-bromoalkane ...