A New Stereocontrolled Approach to a Key Intermediate in the Synthesis of (2S, 3R)-Capreomycidine

…, J Gonda, M Dzoganova

Index: Martinkova, Miroslava; Gonda, Jozef; Dzoganova, Martina Collection of Czechoslovak Chemical Communications, 2006 , vol. 71, # 8 p. 1199 - 1210

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Abstract

The synthesis of enantiopure nonproteinogenic α-amino acids is of great importance due to their role as pharmaceuticals, chiral ligands and building blocks in the synthesis of natural products1. Among recent developments in the preparation of such compounds, the functionalization of readily available proteinogenic α-amino acids and their derivatives has become an atractive method.