Efficient Synthesis of Symmetrical α, α-Disubstituted β-Amino Acids and α, α-Disubstituted Aldehydes via Dialkylation of Nucleophilic β-Alanine Equivalent

D Lin, G Deng, J Wang, X Ding, H Jiang…

Index: Bull, Steven D.; Davies, Stephen G.; Nicholson, Rebecca L.; Sanganee, Hitesh J.; Smith, Andrew D. Organic and Biomolecular Chemistry, 2003 , vol. 1, # 16 p. 2886 - 2899

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Citation Number: 6

Abstract

... The Journal of Organic ... The combined organic layers were dried with MgSO 4 , concentrated, and purified by column chromatography on silica gel (dichloromethane/ methanol = 100 ... Acid Schiff Base Complex 3a: dark red solid; 1 H NMR (CDCl 3 , 300 MHz) δ 8.22 (d, J = 8.4 Hz ...