cis-Nitromethylene neonicotinoids as new nicotinic family: Synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo [1, 2-α] pyridine

X Shao, W Zhang, Y Peng, Z Li, Z Tian…

Index: Shao, Xusheng; Zhang, Wenwen; Peng, Yanqing; Li, Zhong; Tian, Zhongzhen; Qian, Xuhong Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 24 p. 6513 - 6516

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Citation Number: 61

Abstract

A series of neonicotinoids analogues of hexahydroimidazo [1, 2-α] pyridine were modified at 5-, 6-, and 7-positions, and their insecticidal activities were evaluated. Introducing a methyl or ethyl at 7-position increased the insecticidal activities, while other substituents decreased activities. When alkyl substituents were introduced to 7-position, the insecticidal activities against Pea aphids decreased in the order methyl (7a)> ethyl (7b)> n-butyl (7e)> phenyl ( ...