The Journal of Organic Chemistry

Synthetic approaches to 4-spiro-2-hydroxytetronic acids

DT Witiak, AK Tehim

Index: Witiak, Donald T.; Tehim, Ashok K. Journal of Organic Chemistry, 1987 , vol. 52, # 11 p. 2324 - 2327

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Citation Number: 16

Abstract

Tetronic acids are components of numerous natural products, 2 including chl~ rothricin,"~(-)- vertinolide, 6 ircinianin: hippospongin,'and ionophore M 139603, 8 of contemporary interest. The aci-reductone 2-hydroxytetronic acid system 1 found in chl~ rothricin~~~ and ascorbic acid2 has received considerably less attention. Discovery