We envisaged that the 1,2,2-trisubstituted indane derivatives can be assembled by reaction of an active methylene compound with an o-halomethyl cinnamate derivative employing a tandem alkylation-Michael addition sequence (Scheme [1] ). Here, it was anticipated that the active methylene compound will first undergo intermolecular S N 2 substitution reaction followed by intramolecular Michael addition reaction leading to the desired target. To test our hypothesis, we ...
![[2-(chloromethyl)phenyl]methanol Structure](https://image.chemsrc.com/caspic/473/142066-41-9.png)
