Paradigm shift in discovering next-generation anti-infective agents: targeting quorum sensing, c-di-GMP signaling and biofilm formation in bacteria with small …

…, JAI Smith, J Wang, S Nakayama, L Yan

Index: Stacy, Danielle M.; Le Quement, Sebastian T.; Hansen, Casper L.; Clausen, Janie W.; Tolker-Nielsen, Tim; Brummond, Jacob W.; Givskov, Michael; Nielsen, Thomas E.; Blackwell, Helen E. Organic and Biomolecular Chemistry, 2013 , vol. 11, # 6 p. 938 - 954

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Citation Number: 97

Abstract

... Other small molecules such as L-phenylalanine-L-arginine-β-naphthylamine and carbonyl cyanide m-chlorophenylhydrazone (CCCP) have also been shown to inhibit the efflux of drugs such as levofloxacin and faropenam from bacterial cells [37,38]. ...