Tetrahedron Letters

Regioselective photochemical cycloaddition of enamine-carbaldehydes and alkenes; synthesis of 1, 4-Dihydropyridines and 2-hydroxy-1, 2, 3, 4-tetrahydropyridines

LF Tietz, A Bergmann, K Brüggemann

Index: Tietze, Lutz F.; Bergmann, Andreas; Brueggemann, Klaus Tetrahedron Letters, 1983 , vol. 24, # 34 p. 3579 - 3582

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Citation Number: 8

Abstract

Abstract Photocycloaddition of enamine-carbaldehydes 1 and alkenes 2 with an electron- withdrawing or an electron-donating group 2 af and 2 gh regioselectively yields and 4- substituted and the 3-substituted 2-hydroxy-1, 2, 3, 4-tetrahydropyridines 3 respectively. Dehydratisation of 3 with electron-withdrawing groups at C-4 gives the 1, 4-dihydropyridines 4.