Tetrahedron letters

A simple and efficient hydrodehalogenation of 1, 1-dihalocyclopropanes

R Juma'a, MS Baird, IG Bolesov, V Tveresovsky…

Index: Dulayymi, Juma'a R. Al; Baird, Mark S.; Bolesov, Ivan G.; Tveresovsky, Viacheslav; Rubin, Michael Tetrahedron Letters, 1996 , vol. 37, # 49 p. 8933 - 8936

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Citation Number: 24

Abstract

1, 1-Dibromo-and 1, 1-dichlorocyclopropanes are converted into the corresponding monohalo-cyclopropanes (as mixtures of stereoisomers where appropriate) by reaction with 1.2–1.3 mol. equiv. of ethyl magnesium bromide and a small amount of titanium isopropoxide in ether. In the presence of an excess of ethylmagnesium bromide the product from the dibromide is the non-halogenated cyclopropane.