... Journal of the American Chemical Society 1 101:26 ... The successful conversion of 16 to 2 inspired us to use the same approach to the synthesis of the enantiomers of trofos- phamide (3). Reaction of 1(S) and 1(R) with chloroacetyl chloride gave 2- [bis(2-chloroethyl)amino]-3 ...
![(R)-2-aziridin-1-yl-3-((R)-1-phenyl-ethyl)-[1,3,2]oxazaphosphinane 2-oxide Structure](https://image.chemsrc.com/caspic/473/72578-61-1.png)
![3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide Structure](https://image.chemsrc.com/caspic/266/72578-71-3.png)
![(2-chloro-ethyl)-[(S)-2-oxo-3-((R)-1-phenyl-ethyl)-2λ5-[1,3,2]oxazaphosphinan-2-yl]-amine Structure](https://image.chemsrc.com/caspic/207/72578-68-8.png)
![(2-chloro-ethyl)-[(R)-2-oxo-3-((R)-1-phenyl-ethyl)-2λ5-[1,3,2]oxazaphosphinan-2-yl]-amine Structure](https://image.chemsrc.com/caspic/245/72578-67-7.png)
