Hyperproduction of sebaceous cis-6-hexadecenoic acid by esterase-reduced mutant of Rhodococcus sp. strain

…, Y Tsujino, K Koike, S Kawai, K Ozaki, S Ito

Index: Koike; Takaiwa; Kimura; Inoue; Ito Bioscience, biotechnology, and biochemistry, 2000 , vol. 64, # 5 p. 1064 - 1066

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Abstract

cis-6-Hexadecenoic acid is a major component of human sebaceous lipids that is involved in skin self-sterilization and atopic dermatitis amelioration. It can be prepared by hydrolysis of isopropyl cis-6-hexadecenoate produced by resting cells of Rhodococcus sp. strain KSM-