e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedron
Study of the catalytic properties of tris (3, 6-dioxaheptyl) amine (TDA-1) in heteroaromatic nucleophilic substitution of chloropyridines and their N-oxides
Catalytic properties of tris (3, 6-dioxaheptyl) amine (TDA-1) have been analyzed in reactions of alkoxydehalogenation of 2-and 4-chloropyridine and their N-oxides under solid-liquid phase transfer catalysis conditions. Alkoxypyridines were obtained in excelent yields but with N-oxides a competitive alkaline cleavage of the performed ether was observed.
