Potential antitumor agents. 9. 2-Formyl (m-amino) phenylpyridine thiosemicarbazones

KC Agrawal, AJ Lin, BA Booth…

Index: Agrawal,K.C. et al. Journal of Medicinal Chemistry, 1974 , vol. 17, p. 631 - 635

Full Text: HTML

Citation Number: 35

Abstract

Several m-nitro-and m-aminophenyl-substituted 2-formylpyridine thiosemicarbazones have been synthesized. m-Nitrophenyl-2-picolines were formed by coupling 2-picoline with diazotized m-nitroaniline. The 3-, 4-, 5-, and 6-substituted n-nitrophenyl-2-picolines were separated by fractional crystallization and their structures confirmed by nmr. These derivatives were then converted to N-oxides and allowed to react with AczO to form ...