Discovery of potent and selective nonsteroidal indazolyl amide glucocorticoid receptor agonists

JE Sheppeck, JL Gilmore, HY Xiao, TGM Dhar…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 19 p. 5442 - 5447

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Citation Number: 7

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... The indazoles in this and the accompanying Letter were all synthesized from the common synthetic intermediate 5- hydroxymethylindazole (Scheme 1) prepared using the method of Sun et al. ...

4-(1H-Indazol-5-yl)-6-phenylpyrimidin-2 (1H)-one analogs as ...

[Shafer, Cynthia M.; Lindvall, Mika; Bellamacina, Cornelia; Gesner, Thomas G.; Yabannavar, Asha; Jia, Weiping; Lin, Song; Walter, Annette Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 16 p. 4482 - 4485]