Liebigs Annalen der Chemie

Pyridazines, LX. Telesubstitution and Dismutation Reactions in the Series of Phenyl??3??pyridazinylmethane Derivatives

G Heinisch, T Huber

Index: Heinisch, Gottfried; Huber, Thierry Liebigs Annalen der Chemie, 1992 , # 1 p. 19 - 22

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Citation Number: 10

Abstract

Abstract Reactions of 3-α-chlorobenzylpyridazine (4) with alkoxides have been found to yield 6-substituted or 4-substituted 3-benzylpyridazines (7a–c, 8a–c) rather than the usual ethers (6a–c). Introduction of an electron-donating substituent into the 6-position of the pyridazine nucleus of 4 has been shown to suppress such telesubstitution processes. With phenyl-3-pyridazinylmethanol (3), thermally induced dismutation affording 3- ...