Synthesis and histamine H2-antagonist activity of 4-quinazolinone derivatives.

小川信男， 吉田敏彦， 荒谷隆幸， 越中栄一…

Index: Chemical and pharmaceutical bulletin, , vol. 36, # 8 p. 2955 - 2967

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Citation Number: 17

Abstract

... 2956 Vol. 36 (1988) effects. ... This paper describes the synthesis and pharmacological activity of 5. Chemistry At first, we prepared Sa—d (shown in Chart 2) to find the best basic structure for 5. These compounds were obtained by the thermal condensation of amines (6aAd)2'5 ...