e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Helvetica Chimica Acta
Stereochemistry of the σ??Complex Intermediate in Sterically Hindered Electrophilic Aromatic Substitutions.(20th communication on diazo coupling reactions)
Abstract The kinetics of the diazo coupling reactions of diazotized sulfanilic acid with 9 derivatives of 2-naphthol, each containing a substituent in the 8-position, have been measured. The reactions proceed by general base catalysis. The rate constants (k 1) for the formation of the steady-state intermediate in the presence of varying concentrations of a base (pyridine) have been evaluated from rate measurements. Similarly the ratios k 2/k 1 ( ...
